Pipeline

In order to demonstrate the diversity of the AMR-dedicated SMEs’ pipeline in Europe, the BEAM Alliance has collated its members’ technological assets into a comprehensive portfolio. While its size is already impressive, the proposed categorization approach is further revealing the high level of innovativeness that is being deployed, both at clinical and preclinical stages.

Pipeline Rx

Click on column headers to sort the table

memberproductbictypetargetinnovation
criteria		development
stage
PhagoMed Biopharma GmbHPM-4773aProtein/PeptidePrecise Pathogen ID
 
Endolysin specific to bacteria of the genus Gardnerella to treat Bacterial Vaginosis		New TargetLead opt
Nabriva Therapeutics GmbHBC-21263aNMEGram -
Priority Pathogen *
Respiratory tract infections caused by P. aeruginosa, A. baumannii and Burkholderia cepacia complex		New Class
New MoA		Pre-clinical
Nabriva Therapeutics GmbHBC-70133aNMEBroad Gram +/-
Priority Pathogen *
Topical treatment of skin and skin structure infections		Phase I
Destiny Pharma plcXF-733aNMEBroad Gram +/-
Priority Pathogen *
Dermal wound infections		New Class
New Target
New MoA		Phase I
Combioxin SACX1954aOtherGram -
Priority Pathogen *
Severe Gram- resistant infections		New Class
New Target
New MoA		Lead opt
AlaxiaALX-0093aOtherBroad Gram +/-
Priority Pathogen *
Bronchiectasis		New Class
New Target
New MoA		Phase I
AiCuris Anti-infective Cures GmbHNPI Scaffolds3aNMEGram -
Priority Pathogen *
Undisclosed		New Class
New Target
New MoA		Discovery
AiCuris Anti-infective Cures GmbHMacrocyles3aNMEGram -
Priority Pathogen *
Undisclosed		New Class
New Target
New MoA		Discovery
Juvabis AGJUV-3853aNMEBroad Gram +/-
Priority Pathogen *
Systemic Gram-negative, Gram-positive and mycobacterial infections by multidrug-resistant pathogens, including cUTI, BSI, cIAI, HAP/VAP.		Lead opt
Juvabis AGEBL-10033aNMEBroad Gram +/-
Priority Pathogen *
Systemic Gram-negative infections by multidrug-resistant pathogens, including cUTI, BSI, cIAI, HAP/VAP		Phase I
MaaT PharmaMaaT0333cOtherBroad Gram +/-
Priority Pathogen *
Acute Myeloid Leukemia		New Class
New Target
New MoA		Phase I
MaaT PharmaMaaT0133cOtherBroad Gram +/-
Priority Pathogen *
GvHD		New Class
New Target
New MoA		Phase II
MaaT PharmaMaaT0125bOtherBroad Gram +/-
 
Acute Myeloid Leukemia		New Class
New Target
New MoA		Phase II
Basilea Pharmaceutica International Ltd.undisclosed3aNMEGram -
Priority Pathogen *
Serious infections in hospitalized patients 		New ClassLead opt
Basilea Pharmaceutica International Ltd.Non beta-lactam PBP inhibitor3aNMEGram -
Priority Pathogen *
Serious infections in hospitalized patients 		New ClassLead opt
Pherecydes PharmaPP11513aPhagePrecise Pathogen ID
Priority Pathogen *
MDR infections to Escherichia coli		New Class
New MoA		Pre-clinical
Pherecydes PharmaPP10023aPhagePrecise Pathogen ID
Priority Pathogen *
MDR infections to Escherichia coli		New Class
New MoA		Pre-clinical
Pherecydes PharmaPP9703aPhagePrecise Pathogen ID
Priority Pathogen *
MDR infections to Escherichia coli		New Class
New MoA		Pre-clinical
Pherecydes PharmaPP9543aPhagePrecise Pathogen ID
Priority Pathogen *
MDR infections to Escherichia coli		New Class
New MoA		Pre-clinical
Pherecydes PharmaPP8143aPhagePrecise Pathogen ID
Priority Pathogen *
MDR infections to Escherichia coli		New Class
New MoA		Pre-clinical
Pherecydes PharmaPP7003aPhagePrecise Pathogen ID
Priority Pathogen *
MDR infections to Escherichia coli		New Class
New MoA		Pre-clinical
Assuré Medical LimitedSol-UTI1bOtherGram -
Priority Pathogen *
Recurrent Urinary Tract Infection (rUTI)		New Target
New MoA		Pre-clinical
BioVersys AGBV1003aNMEGram -
Priority Pathogen *
A. baumannii (HAP,VAP, BSI)		New MoAPre-clinical
Madam Therapeutics BVP103aProtein/PeptideBroad Gram +/-
Priority Pathogen *
Veterinary Diseases (companion animals and lifestock)		New Class
New Target
New MoA		Pre-clinical
Destiny Pharma plcDPD-2073aNMEGram +
Priority Pathogen *
MDR bacterial eye infections		New Class
New Target
New MoA		Pre-clinical
AlphanososW9P1543eOtherPrecise Pathogen ID
Priority Pathogen *
Tuberculosis, Buruli Ulcer		New Class
New Target
New MoA		Lead opt
ABAC therapeuticsABAC-40,2443aNMEPrecise Pathogen ID
Priority Pathogen *
Infections by MDR/XDR Staph aureus		New Class
New Target
New MoA		Lead opt
ABAC therapeuticsABAC-401053aNMEGram -
Priority Pathogen *
Infections by MDR/XDR A baumannii, including ColistinR and CarbapenemR		New Class
New Target
New MoA		Lead opt
ANTABIO S.A.SANT33103dNMEGram -
Priority Pathogen *
Hospital-acquired infections caused by carbapenem-resistant Enterobacteriaceae (CRE) and Acinetobacter [cUTI, cIAI, Nosocomial Pneumonia]		New MoALead opt
VibioSphenSativa3bNME 
 
Pulmonary infection, UTI		Pre-clinical
VAXDYNVXD-0021aVaccinePrecise Pathogen ID
Priority Pathogen *
Hospital/community acquired untreatable or difficult-to-treat infections, caused by Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter baumannii		New Class
New Target
New MoA		Lead opt
VAXDYNVXD-0033cAntibodyPrecise Pathogen ID
Priority Pathogen *
Hospital/community acquired untreatable or difficult-to-treat infections, caused by Acinetobacter baumannii		New Class
New Target
New MoA		Lead opt
VAXDYNVXD-0011aVaccinePrecise Pathogen ID
Priority Pathogen *
Hospital/community acquired untreatable or difficult-to-treat infections, caused by Acinetobacter baumannii		New Class
New Target
New MoA		Pre-clinical
Summit Therapeutics plcSMT0265713aNMEGram -
Priority Pathogen *
Gonorrhoea infection		New Class
New Target
New MoA		Pre-clinical
Summit Therapeutics plcRidinilazole3aNMEGram +
Priority Pathogen *
Clostridium difficile infection		New Class
New Target
New MoA		Phase III
SetLance srlSET-M333aProtein/PeptideBroad Gram +/-
Priority Pathogen *
Sepsis, pneumonia and skin infections		Pre-clinical
QureTech Bio ABTIB3aNMEPrecise Pathogen ID
 
Trachoma, Chlamydia eye infection		New Class
New Target
New MoA		Lead opt
QureTech Bio ABGmP3dNMEGram +
Priority Pathogen *
VRE and MRSA		New Class
New Target
New MoA		Lead opt
QureTech Bio ABCIB3aNMEPrecise Pathogen ID
Priority Pathogen *
Genital Chlamydia infection		New Class
New Target
New MoA		Lead opt
QureTech Bio ABMTI3dNMEPrecise Pathogen ID
Priority Pathogen *
MDR Tuberculosis		New Class
New Target
New MoA		Pre-clinical
PureIMS BVTobramycin Cyclops™3aOtherGram -
Priority Pathogen *
Cystic Fibrosis		Phase I
PureIMS BVIsoniazid Cyclops™3aOtherBroad Gram +/-
Priority Pathogen *
Tuberculosis		IND/CTA ready
PureIMS BVLinezolid Cyclops™3aOtherBroad Gram +/-
Priority Pathogen *
Tuberculosis		IND/CTA ready
PureIMS BVAmikacin Cyclops™3aOtherGram -
Priority Pathogen *
Multidrug-resistant tuberculosis (MDR-TB)		IND/CTA ready
PureIMS BVColistin Cyclops™3aProtein/PeptideGram -
Priority Pathogen *
Cystic Fibrosis		Marketed
Polyphor LtdMurepavadin (inhaled)3aProtein/PeptideGram -
Priority Pathogen *
Cystic Fibrosis; Bronchiectasis		New Class
New Target
New MoA		Pre-clinical
Polyphor LtdOMPTA3aProtein/PeptideGram -
Priority Pathogen *
HAP, VAP, UTI, IAI, other		New Class
New Target
New MoA		Pre-clinical
Phico Therapeutics LtdSASPject™ PT43aOtherPrecise Pathogen ID
Priority Pathogen *
Serious Klebsiella Pneumoniae infections where treatment options are limited		New Target
New MoA		Pre-clinical
Phico Therapeutics LtdSASPject™ PT53aOtherPrecise Pathogen ID
Priority Pathogen *
Serious E.coli infections where treatment options are limited		New Target
New MoA		Pre-clinical
Phico Therapeutics LtdSASPject™ PT3.83aOtherPrecise Pathogen ID
Priority Pathogen *
Serious Pseudomonas Aeruginosa infections where treatment options are limited		New Target
New MoA		Pre-clinical
Pherecydes PharmaPN17773aPhagePrecise Pathogen ID
Priority Pathogen *
MDR infections to Pseudomonas aeruginosa		New Class
New MoA		Pre-clinical
Pherecydes PharmaPN17923aPhagePrecise Pathogen ID
Priority Pathogen *
MDR infections to Pseudomonas aeruginosa		New Class
New MoA		Pre-clinical
Pherecydes PharmaPN17973aPhagePrecise Pathogen ID
Priority Pathogen *
MDR infections to Pseudomonas aeruginosa		New Class
New MoA		Pre-clinical
Pherecydes PharmaPN14933aPhagePrecise Pathogen ID
Priority Pathogen *
MDR infections to Staphylococcus aureus		New Class
New MoA		Pre-clinical
Pherecydes PharmaPN18153aPhagePrecise Pathogen ID
Priority Pathogen *
MDR infections to Staphylococcus aureus		New Class
New MoA		Pre-clinical
Pherecydes PharmaPN19573aPhagePrecise Pathogen ID
Priority Pathogen *
MDR infections to Staphylococcus aureus		New Class
New MoA		Pre-clinical
Pherecydes PharmaPN14503aPhagePrecise Pathogen ID
Priority Pathogen *
MDR infections to Pseudomonas aeruginosa		New Class
New MoA		Pre-clinical
PhagoMed Biopharma GmbHPhM3983aPhagePrecise Pathogen ID
Priority Pathogen *
Periprosthetic Joint Infections		New Class
New MoA		Lead opt
PhagoMed Biopharma GmbHPhM7543aPhagePrecise Pathogen ID
Priority Pathogen *
Urinary Tract Infections		New Class
New MoA		Lead opt
Omnix MedicalOMN63aProtein/PeptideGram -
Priority Pathogen *
A. baumannii induced Bacteremia or HABP or VABP		New Class
New MoA		Lead opt
NovaBiotics LtdNovamycin®3aProtein/PeptideNon Bacterial Target
Priority Pathogen *
Invasive Fungal Disease, mucocutaneous fungal infections		New Class
New Target
New MoA		Pre-clinical
NovaBiotics LtdNylexa™3dOtherBroad Gram +/-
Priority Pathogen *
Resistance breaker		New Class
New Target
New MoA		Pre-clinical
NovaBiotics LtdNovarifyn®3aProtein/PeptideBroad Gram +/-
Priority Pathogen *
Gram negative and Gram negative reistant/MDR infections (ESKAPE), some Gram positive coverage		New Class
New Target
New MoA		Pre-clinical
NovaBiotics LtdLuminaderm®1bProtein/PeptideBroad Gram +/-
Priority Pathogen *
MRSA		New Class
New Target
New MoA		Pre-clinical
NovaBiotics LtdLynovex® inhaled1aOtherBroad Gram +/-
Priority Pathogen *
Cystic Fibrosis		New Class
New Target
New MoA		IND/CTA ready
NovaBiotics LtdNovexatin®3aProtein/PeptideNon Bacterial Target
Priority Pathogen *
Onychomycosis		New Class
New Target
New MoA		Phase II
NovaBiotics LtdLynovex® oral3bOtherBroad Gram +/-
Priority Pathogen *
Cystic Fibrosis		New Class
New Target
New MoA		Phase II
NosopharmNOSO-A43aNMEBroad Gram +/-
Priority Pathogen *
P. aeruginosa infections		New Class
New Target
New MoA		Discovery
NosopharmNOSO-5023aNMEGram -
Priority Pathogen *
MDR Enterobacteriaceae infections		New Class
New Target
New MoA		Pre-clinical
Northern Antibiotics Oy (Ltd)NAB8153aProtein/PeptideGram -
Priority Pathogen *
cUTI caused by MDR Gram-negatives		Pre-clinical
Northern Antibiotics Oy (Ltd)NAB7393aProtein/PeptideGram -
Priority Pathogen *
cUTI caused by MDR Gram-negatives		Pre-clinical
Neem Biotech LtdNX-AS-9115aNMEBroad Gram +/-
Priority Pathogen *
Treatment of infected wounds (P. aeruginosa, S. aureus), inlcuding those with a biofilm presence.		New Class
New MoA		Pre-clinical
Neem Biotech LtdNX-AS-4015aNMEGram -
Priority Pathogen *
Treatment of chronic P. aeruginosa lung infection in people with cystic fibrosis		New Class
New MoA		Pre-clinical
Nabriva Therapeutics GmbHLefamulin3aNMEBroad Gram +/-
Priority Pathogen *
ABSSSI		New Class
New Target
New MoA		Phase II
Nabriva Therapeutics GmbHLefamulin3aNMEBroad Gram +/-
Priority Pathogen *
STIs, HABP/VABP, Osteomyelitis, Prosthetic Joint Infections		New Class
New Target
New MoA		Pre-clinical
Nabriva Therapeutics GmbHLefamulin3aNMEBroad Gram +/-
Priority Pathogen *
Pediatric Indications		New Class
New Target
New MoA		Phase I
Nabriva Therapeutics GmbHLefamulin3aNMEBroad Gram +/-
Priority Pathogen *
CABP (community-acquired bacterial pneumonia)		New Class
New Target
New MoA		Phase III
Mutabilis SAS2G-DABOCIN3aNMEGram -
Priority Pathogen *
IV treatment against Enterobacterales & non-fermenters		New ClassLead opt
Mutabilis SASC3G/EBL-22533dNMEGram -
Priority Pathogen *
Oral Betalactamases inhibitor in combi with cephalosporine		Pre-clinical
Mutabilis SASEBL-14633aNMEGram -
Priority Pathogen *
IV treatment against Enterobacterales		New ClassPre-clinical
Madam Therapeutics BVSAAP1483aProtein/PeptideBroad Gram +/-
Priority Pathogen *
Diabetic foot ulcers, burns and MRSA carriership		New Class
New Target
New MoA		Pre-clinical
MaaT PharmaMaaT0115aOtherBroad Gram +/-
 
Acute Myeloid Leukemia		New Class
New Target
New MoA		Phase II
MaaT PharmaMaaT0311bOtherBroad Gram +/-
 
Bone and Joint Infectious		New Class
New Target
New MoA		Phase I
IMMUNETHEP, SAUnimab3cAntibodyBroad Gram +/-
Priority Pathogen *
Intensive Care Units / Hospital Acquired infections		New Class
New Target
New MoA		Pre-clinical
IMMUNETHEP, SAcPNV1aVaccineBroad Gram +/-
Priority Pathogen *
Preventive		New Class
New Target		Pre-clinical
Hypharm GmbHHY-1331bPhageGram +
Priority Pathogen *
Nasal colonization with MRSA		New Class
New Target
New MoA		Pre-clinical
Helperby Therapeutics LtdHY-0013dOtherGram -
Priority Pathogen *
Urinary Tract Infections		New Class
New Target
New MoA		Phase II
Helperby Therapeutics LtdHY-0023dOtherGram -
Priority Pathogen *
Intra-Abdominal Infections		New Class
New Target
New MoA		Phase I
Helperby Therapeutics LtdHY-0041bOtherGram +
Priority Pathogen *
Nasal MRSA decolonisation		New Class
New Target
New MoA		Phase II
Helperby Therapeutics LtdHY-0053dOtherGram +
Priority Pathogen *
Skin & Soft Tissue MRSA		New Class
New Target
New MoA		Phase II
Eligo BioscienceEB0041bOtherPrecise Pathogen ID
Priority Pathogen *
Multi-drug resistant Enterobacteriaceae		New Class
New MoA		Pre-clinical
Destiny Pharma plcXF-733dNMEBroad Gram +/-
Priority Pathogen *
Hospital pneumonia/ventilator-associated pneumonia (VAP)		New Class
New Target
New MoA		Pre-clinical
Destiny Pharma plcXF-701bNMEBroad Gram +/-
Priority Pathogen *
Bacterial biofilm-infections		New Class
New Target
New MoA		Pre-clinical
Destiny Pharma plcXF-731bNMEBroad Gram +/-
Priority Pathogen *
Prevention of post-surgical infection		New Class
New Target
New MoA		Phase II
DEINOVEDNV38373aNMEBroad Gram +/-
Priority Pathogen *
C.difficile gastrointestinal infections		New Class
New MoA		Phase II
Debiopharm InternationalDebio 14533aNMEGram -
Priority Pathogen *
N. gonorrhoeae		New Class
New Target
New MoA		Discovery
Debiopharm InternationalAfabicin (Debio 1450)3aNMEPrecise Pathogen ID
Priority Pathogen *
ABSSSI, Bone & Joint Infections (BJIs)		New Class
New Target
New MoA		Phase II
Combioxin SACAL024aOtherBroad Gram +/-
Priority Pathogen *
Severe infections		New Class
New Target
New MoA		Phase II
Centauri Therapeutics LtdABX013cOtherGram -
Priority Pathogen *
Broad spectrum Gram negative, including clinically-relevant strains of Enterobacteriaceae, P. aeruginosa, and A. baumannii		New Class
New Target
New MoA		Pre-clinical
Centauri Therapeutics LtdABX023cOtherPrecise Pathogen ID
Priority Pathogen *
Pseudomonas Aeruginosa specific Inhibitor		New Class
New Target
New MoA		Pre-clinical
BioVersys AGBV2004aNMEGram +
Priority Pathogen *
Anti-toxin for Staphylococcus aureus		New Class
New Target
New MoA		Lead opt
BioVersys AGBV4003bNMEGram -
Priority Pathogen *
Anti Virulence in Gram negative bacteria, Enterobacteriaceae and A. baumannii		New Class
New Target
New MoA		Lead opt
BioVersys AGBVL-GSK0X83dNMEPrecise Pathogen ID
Priority Pathogen *
Adjuvant reversing resistance and potentiating Ethionamide activity in Tuberculosis		New Class
New Target
New MoA		Pre-clinical
BioFilm PharmaBFP0023eNMEBroad Gram +/-
Priority Pathogen *
Staphylococcus aureus, Pseudomonas aeruginosa Systemic – Cystic Fibrosis		New Target
New MoA		Lead opt
BioFilm PharmaBFP1013eNMEGram +
Priority Pathogen *
Staphylococcus aureus Local - Diabetic Foot Ulcer, Joint & Bone Infections		New Target
New MoA		Lead opt
BioFilm PharmaBFP1023eNMEBroad Gram +/-
Priority Pathogen *
Staphylococcus aureus, Pseudomonas aeruginosa Systemic – Cystic Fibrosis		New Class
New Target
New MoA		Lead opt
BioFilm PharmaBFP0013eNMEGram +
Priority Pathogen *
Staphylococcus aureus Local - Diabetic Foot Ulcer, Joint & Bone Infections		New Class
New Target
New MoA		Lead opt
Basilea Pharmaceutica International Ltd.Ceftobiprole3aNMEBroad Gram +/-
Priority Pathogen *
Acute bacterial skin and skin structure infections, Staphylococcus aureus bacteremia		Phase III
Basilea Pharmaceutica International Ltd.Ceftobiprole3aNMEBroad Gram +/-
Priority Pathogen *
Community- and hospital-acquired pneumonia (excluding ventilator-associated pneumonia)		Marketed
ANTABIO S.A.SANT_Pei3cNMEPrecise Pathogen ID
Priority Pathogen *
Pseudomonas infections in Cystic Fibrosis patients		New Class
New Target
New MoA		Lead opt
ANTABIO S.A.SANT26813dNMEGram -
Priority Pathogen *
Hospital-acquired infections caused by carbapenem-resistant Enterobacteriaceae (CRE) [cUTI, cIAI, Nosocomial Pneumonia]		New Class
New Target
New MoA		Pre-clinical
AlphanososW16P05763eOtherBroad Gram +/-
Priority Pathogen *
A. baumannii, P. aeruginosa, MRSA,N. gonorrhoeae, M. tuberculosis - Infectious skin conditions (eczema, acne, sporiasis, ...), difficult wounds		New Class
New Target
New MoA		Pre-clinical
ALLECRA THERAPEUTICSCefepime / Enmetazobactam3dNMEBroad Gram +/-
Priority Pathogen *
cUTI, cIAI, HAP		Phase II
AlaxiaALX-0093aOtherBroad Gram +/-
Priority Pathogen *
Cystic Fibrosis		New Class
New Target
New MoA		Phase I
AktheliaHO53/HO56 ADP3cNMEBroad Gram +/-
Priority Pathogen *
Multidrug resistant lung infections including nosocomial infections (K. pneumoniae)		New Class
New Target
New MoA		Lead opt
AiCuris Anti-infective Cures GmbHArtilysins3aProtein/PeptideGram -
Priority Pathogen *
Undisclosed		New Class
New MoA		Lead opt
AGILeBiotics B.V.ABX-3953aNMEGram -
Priority Pathogen *
Hospital-treated MDR Gram-negative infections		Lead opt
AGILeBiotics B.V.ABX-6053aNMEGram -
Priority Pathogen *
Hospital-treated MDR Gram-negative infections		Lead opt
ABAC therapeuticsABAC-39,8773aNMEGram -
Priority Pathogen *
Infections by MDR/XDR A baumannii, including ColistinR and CarbapenemR		New Class
New Target
New MoA		Pre-clinical
Da VolterraDAV1214bOtherBroad Gram +/-
Priority Pathogen *
Prevention of gut microbiota antibiotic-dysbiosis and emergence of resistance to β-lactam antibiotics, including carbapenems		New Class
New Target
New MoA		Lead opt
Da VolterraDAV1324bOtherBroad Gram +/-
Priority Pathogen *
Prevention of C.difficile infections		New Class
New Target
New MoA		Phase II
PreviousPage 1/13show allNext

*Priority pathogens have been listed by WHO and CDC

The displayed information are not necessarily reflecting the official current position of each BEAM members; please refer to each company’s website for updated information, or contact them directly.

Pipeline Dx

Click on column headers to sort the table

memberkit/testtargeted resultpathogens & indicationslab workflowdevelopment stage
FASTinov SAFAST MIC colistineAST PhenotypingIncl. Priority Pathogens
Enterobacterales
From PBS + Isolated colony
Flow cytometer
<2h		Feasibility Phase
FASTinov SAFAST MIC colistineAST PhenotypingIncl. Priority Pathogens
Enterobacterales
From urine
Flow cytometer
<2h		Feasibility Phase
FASTinov SAFAST panel urineAST PhenotypingIncl. Priority Pathogens
Gram negative/Gram positive and main mechanisms of resitance
From urine
Flow cytometer
<2h		Feasibility Phase
FASTinov SAFAST panel marAST PhenotypingIncl. Priority Pathogens
For detection of main mechanisms of resistance: ESBLs, AmpC and carbapenemases
From positive blood culture
Flow cytometer
<2h		Clinical Validation EU and/or US
Fast BTUTI ASTAST Phenotyping 
Escherichia coli, Klebsiella species, Proteus species, Pseudomonas aeruginosa,
From urine
Microplate-reader
<6h		Feasibility Phase
Fast BTSepsis ASTAST PhenotypingIncl. Priority Pathogens
Escherichia coli, Klebsiella spp. Enterobacter spp. Proteus spp. Salmonella typhi, Salmonella spp. other than S. typhi Pseudomonas aeruginosa, Neisseria meningitidis
From whole blood
Microplate-reader
<6h		Feasibility Phase
Fast BTSepsis IDPathogen IDIncl. Priority Pathogens
Escherichia coli, Klebsiella spp. Enterobacter spp. Proteus spp. Salmonella typhi, Salmonella spp. other than S. typhi Pseudomonas aeruginosa, Neisseria meningitidis
From whole blood
Microplate-reader
<30 minutes		Feasibility Phase
Nemis Technologies AGClinDxAST PhenotypingIncl. Priority Pathogens
Carbapenemase producing bacteria
Patient admission screening		From Swab
Other supporting Techno
<4h		Development Phase
NG BiotechNG-Test CTX-MAST PhenotypingIncl. Priority Pathogens
Enterobacteriaceae
Rapid test for the detection of CTX-M groups 1 β-lactamases		From isolated colony
LFIA (Lateral Flow Immuno Assay)
<30 minutes		CE-IVD and/or FDA 510k
NG BiotechNG-Test Blood Culture PrepAST PhenotypingIncl. Priority Pathogens
Enterobacteriaceae
Sample Preparation kit from a positive blood culture		From positive blood culture
Other supporting Techno
<30 minutes		CE-IVD and/or FDA 510k
NG BiotechNG-Test MCR1AST PhenotypingIncl. Priority Pathogens
Enterobacteriaceae
Rapid test for the detection of Colistin resistance		From isolated colony
LFIA (Lateral Flow Immuno Assay)
<30 minutes		CE-IVD and/or FDA 510k
NG BiotechNG-Test CTX-M MULTIAST PhenotypingIncl. Priority Pathogens
Enterobacteriaceae
Rapid test for the detection of CTX-M groups 1, 2, 8, 9, 25 β-lactamases		From isolated colony
LFIA (Lateral Flow Immuno Assay)
<30 minutes		CE-IVD and/or FDA 510k
NG BiotechNG-Test CARBA 5AST PhenotypingIncl. Priority Pathogens
Enterobacteriaceae, carbapenem-resistant; 3rd generation cephalosporin-resistant; A. baumannii, carbapenem-resistant; P. aeruginosa, carbapenem-resistant
Rapid test for the detection of the 5 main Carbapenemases KPC, OXA-like, VIM, IMP and NDM		From isolated colony and From positive blood culture
LFIA (Lateral Flow Immuno Assay)
<30 minutes		CE-IVD and/or FDA 510k
MilliDrop Instrument SASMDI-MICAST PhenotypingIncl. Priority Pathogens
Escherichia coli - Enterobacter Pseudomonas - Acinetobacter
Standard MIC determination for multi-resistant strains and new therapeutic strategies 		From isolated colony
Microfluidic liquid handling
<8h		Feasibility Phase
MilliDrop Instrument SASMDI-SepsisID/AST combinedIncl. Priority Pathogens
Escherichia coli - Klebsiella - Enterobacter - Proteus - Pseudomonas - Haemophilus - Acinetobacter - Staphylococcus - Streptococcus - Candida
Sepsis		From whole blood
Microfluidic liquid handling
<24h		Feasibility Phase
Nanosynex LtdNanosyAST Phenotyping 
 
From isolated colony
Microfluidic chip/reader
<4h		Feasibility Phase
FASTinov SAFAST panel Gram+AST PhenotypingIncl. Priority Pathogens
S. aureus/epidermidis, E. faecalis/faecium/casseliflavus/gallinarum
From positive blood culture
Flow cytometer
<2h		Clinical Validation EU and/or US
FASTinov SAFAST panel Gram-AST PhenotypingIncl. Priority Pathogens
E. coli, K. pneumoniae, E. cloacae/aerogenes, P. aeruginosa, A. baumanii, S. marcescens, P. rettgeri
From positive blood culture
Flow cytometer
<2h		Clinical Validation EU and/or US
BioFilm PharmaAntiBiofilmogram Urinary CareAST PhenotypingIncl. Priority Pathogens
E. coli
Urinary Tract Infections, Catheter Associated Urinary Tract Infections		From isolated colony
Microplate-reader
<4h		Development Phase
BioFilm PharmaAntiBiofilmogram Lung CareAST PhenotypingIncl. Priority Pathogens
Staphylococcus aureus
Cystic Fibrosis		From isolated colony
Microplate-reader
<4h		Prototype in Lab
BioFilm PharmaAntiBiofilmogram Lung CareAST PhenotypingIncl. Priority Pathogens
Pseudomonas aeruginosa
Cystic Fibrosis		From isolated colony
Microplate-reader
<4h		Prototype in Lab
BioFilm PharmaAntiBiofilmogram Wound CareAST PhenotypingIncl. Priority Pathogens
Staphylococcus aureus
Diabetic Foot Ulcer, Joint & Bone Infections		From isolated colony
Microplate-reader
<4h		Clinical Validation EU and/or US
MeMed Diagnostics Ltd.MeMed BV™Viral vs Bacterial 
 
Point-of-need discrimination of the viral/bacterial nature of an infection		From serum/plasma
 
<30 minutes		Clinical Validation EU and/or US
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The displayed information are not necessarily reflecting the official current position of each BEAM members; please refer to each company’s website for updated information, or contact them directly.