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NEWS

Nosopharm obtains US patent for NOSO-502, a first-in-class novel antibiotic

  • Patent secures US market exclusivity for Nosopharm and covers numerous chemical analogs, reinforcing protection of NOSO-502’s chemical space

Lyon, France, April 22, 2020 – Nosopharm, specialized in exploring unconventional sources of antibiotics to discover new drugs to fight antimicrobial resistance, today announces it has been granted a US patent for NOSO-502. NOSO-502 is Nosopharm’s first clinical candidate in a new class of antibiotics called Odilhorhabdins, aimed at eradicating resistant bacteria. This patent secures Nosopharm’s market exclusivity rights in the US, the leading pharmaceutical market. It also covers numerous chemical analogs – the chemical space of NOSO-502 – thereby reinforcing its protection against exploitation by competitors.

Besides the US patent (US Patent No. 10,626,144), Nosopharm has been granted a patent in Russia, and a notice of acceptance has recently been issued in Australia. In addition, the company has filed patent applications in Canada, China, Europe (EPO), Japan, Hong Kong, Brazil, South Korea, India, Israel and Mexico. Apart from Canada and South Korea, which start examining patent applications later than other countries, decisions are pending in all these territories and are expected to be announced during the course of this year.

“The award of a US patent for our clinical candidate NOSO-502 is a key milestone in Nosopharm’s development,” said Philippe Villain-Guillot, co-founder and chief executive officer at Nosopharm. “The US market is the global leader in pharmaceuticals and we have now secured exclusive marketing rights there. Backed by this IP, there is significantly more incentive for both a potential industrial partner to in-license the NOSO-502 program and further developments to combat resistant bacteria.”

The growing resistance of pathogenic bacteria is a threat to the efficacy of antibiotics. In 2015 antibiotic-resistant bacteria were estimated to be responsible for 670,000 infections and 33,110 attributable deaths in the EU and the European Economic Area (EEA). From a global perspective, antimicrobial resistance could kill up to ten million people every year by 2050, which could cost up to €94 trillion ($100tn).

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