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Polyphor announces acceptance of balixafortide abstract at the American Society of Clinical Oncology (ASCO) 2020 virtual scientific program

Allschwil, Switzerland, May 14, 2020

Polyphor AG (SIX: POLN) a research-driven clinical-stage, Swiss biopharmaceutical company committed to discovering and developing first-in-class molecules in oncology and antimicrobial resistance announced today that the abstract “Balixafortide (a CXCR4 antagonist) plus eribulin in HER2 negative metastatic breast cancer: dose-response analysis of efficacy from Phase I single arm trial” has been accepted for the ASCO 2020 Virtual Conference, which is being held from May 29-31. The data, published online on the ASCO Meeting Library, show a consistent dose response of increasing doses of balixafortide in combination with the approved dose of eribulin.

“This analysis published and supported by the steering committee of the study demonstrates an impressive overall efficacy of balixafortide at the dose of 5.5mg/kg in comparison to lower doses of balixafortide and to historical results of eribulin monotherapy in comparable populations. This benefit is observed consistently throughout all efficacy endpoints,” said Peter Kaufman, Professor of Medicine, and Hematology/Oncology, at the University of Vermont Cancer Center and lead author of the abstract. Frank Weber, MD, CMDO of Polyphor adds: “Polyphor is looking forward to the results of the ongoing Phase III study FORTRESS which investigates the efficacy and safety of balixafortide at the 5.5mg/kg dose in combination with eribulin. We have randomized a total of 273 patients by today and plan to complete the enrollment of 384 patients into FORTRESS by September 2020.”

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